This woman is the only one in the world with this medical condition

Mandy Sellars, 41, from Lancashire,  UK, has a condition which causes an overgrowth of skin, bone and tissue. She had one leg amputated but it grew back.

When she was born, Mandy Sellars had legs five times the size of a typical newborn and doctors feared she would never walk.

But she defied them as a toddler and still astonishes them today after her legs continued to grow - even after one was amputated.

The 41-year-old is the only person in the world to suffer from a genetic condition which causes an overgrowth of the skin, bone, fat and tissue in her lower half.

It means she has a trim size-10 upper-body but huge limbs even after having her left leg amputated in 2010 due to blood poisoning.

Astonishingly, the stump started to grow again and within three years measured one metre in circumference and weighed three stone.

With doctors baffled about her condition, she tried to live a normal life by going to school, college and studying psychology at the University of Central Lancashire.

Doctors at Cambridge University carried out series of tests on Miss Sellars' DNA.
They discovered she has a single letter mutation in the PIK3CA gene, causing the overgrowth in her legs and foot.

Miss Sellars was the first person in the world to be discovered with this particular type of gene mutation.

She was given medication to shrink the fatty tissue in her legs and foot and has since lost six stone (over 38kg).

Doctors are unsure if her legs will continue to shrink, but Miss Sellars is keeping a positive attitude.
'People say 'I don't know how you cope', but I am making the most of what I am able to do and feel in who I am. I am proud to be me,' she said.

Image Credit: Channel 5, PA Real Life